Efektivitas In-vivo Gel Peel-Off Mask Berbasis Centella asiatica terhadap Peningkatan Kelembaban Kulit
Keywords:
Peel-off gel mask, Centella asiatica, Natural skin moisturizer, In vivo evaluation, Stability testAbstract
Gel peel-off mask merupakan salah satu bentuk sediaan kosmetik yang semakin populer karena kemampuannya memberikan manfaat ganda, seperti membersihkan permukaan kulit sekaligus memberikan hidrasi. Penelitian ini bertujuan untuk merumuskan, mengevaluasi stabilitas, dan mengkaji efektivitas in vivo dari gel peel-off mask berbahan dasar ekstrak daun pegagan (Centella asiatica) sebagai alternatif pelembap kulit berbahan alami. Studi ini menggunakan metode eksperimental laboratorium dengan empat formula berbeda yang divariasikan berdasarkan konsentrasi Polyvinyl Alcohol (PVA), serta dilakukan uji stabilitas fisik dan uji efektivitas terhadap peningkatan kelembaban kulit selama satu minggu. Hasil menunjukkan bahwa formula dengan PVA 13% dan ekstrak pegagan 5% memiliki karakteristik fisik paling stabil, meliputi pH, viskositas, homogenitas, daya lekat, kecepatan pengeringan, serta memberikan peningkatan kelembaban kulit yang signifikan. Kandungan metabolit sekunder seperti asiaticoside, madecassoside, saponin, dan flavonoid diduga berperan dalam mempertahankan hidrasi kulit melalui mekanisme peningkatan barrier kulit dan stimulasi sintesis kolagen. Formulasi ini juga menunjukkan kesesuaian optimal dengan parameter kenyamanan pengguna. Penelitian ini memberikan kontribusi nyata terhadap pengembangan kosmetik herbal modern dan merekomendasikan studi lanjutan berupa uji klinis jangka panjang pada populasi lebih luas guna validasi lebih lanjut.
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