Perbandingan ekstraksi akar kucing (Acalypha indica l.) dengan ekstrak etanol 96% dan ekstrak akuades terhadap pertumbuhan EPEC dan Candida albicans

Authors

  • Musjaya M. Guli Program Studi Biologi, Fakultas Matematika dan Ilmu Pengentahuan Alam, Universitas Tadulako
  • Yuyun Jannatul Zahra Program Studi Biologi, Fakultas Matematika dan Ilmu Pengentahuan Alam, Universitas Tadulako
  • Muh. Akbar Ardiputra Program Studi Biologi, Fakultas Matematika dan Ilmu Pengentahuan Alam, Universitas Tadulako
  • Agnes Immanuela Toemon Departemen Parasitologi, Fakultas Kedokteran, Universitas Palangka Raya, Palangka Raya, Kalimantan Tengah, Indonesia

DOI:

https://doi.org/10.37304/jkupr.v11i2.11038

Keywords:

Acalypha indica L, zone of inhibition, antimicrobial

Abstract

The root of the cat (Acalypha indica L.) was used as the object of research and extraction was carried out to determine the antimicrobial activity of 96% ethanol extract and distilled water against EPEC (Enterophatogenic Escherichia coli) bacteria and the fungus Candida albicans. The method used for plant sampling is purposive sampling method. Extraction of active compounds using maceration method. The antimicrobial potency test used the agar-diffusion method using two types of microbial pathogens, namely the bacteria EPEC and the fungus Candida albicans. Each paper disk was given 50 µL of bacterial isolate, incubated at 37 0C for 24 hours and continued for 48 hours. The observed parameter is the clear zone formed around the paper disk. The results showed that cat root (A. indica L.) contains compounds that can inhibit the growth of EPEC bacteria and the fungus C. albicans. A good solvent to extract the active compounds contained in the cat root plant (A. indica L.) is distilled water. Treatment with aquadest extract with a concentration of 100% had the widest inhibition zone among other treatments, namely 6.8 mm against the growth of EPEC bacteria and ethanol extract with a concentration of 100% which was 3.8 mm against the growth of the fungus Candida albicans.

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Published

2023-11-03

How to Cite

M. Guli, M., Zahra, Y. J. ., Ardiputra, M. A. ., & Toemon, A. I. (2023). Perbandingan ekstraksi akar kucing (Acalypha indica l.) dengan ekstrak etanol 96% dan ekstrak akuades terhadap pertumbuhan EPEC dan Candida albicans. Jurnal Kedokteran Universitas Palangka Raya, 11(2). https://doi.org/10.37304/jkupr.v11i2.11038