Skrining fitokimia tumbuhan potensi obat kanker kolorektal Begonia medicinalis Ardi & D.C. Thomas

Penulis

  • Muh. Akbar Ardiputra Program Studi Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako
  • Dr. Musjaya M. Guli, S.Si., M.Si. Program Studi Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako
  • Ns. Andi Saifah, M. Kep., Sp. Kep. Kom. Program Studi Keperawatan Fakultas Kedokteran Universitas Tadulako
  • Santi, S.Si. Program Studi Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako
  • Dr. Ir. Bambang Sardi, S.T., M.T. Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako
  • Wafiq Nurfadilah, S.Ked. Program Studi Kedokteran Fakultas Kedokteran Universitas Tadulako
  • Mohammad Rivaldi Putra Pratama Program Studi Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako
  • Afifah Islamia Program Studi Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako

DOI:

https://doi.org/10.37304/jkupr.v12i2.13207

Kata Kunci:

Kanker Kolorektal, Begonia medicinalis Ardi & D.C. Thomas, Flavonoid, Alkaloid, Saponin

Abstrak

Cancer is a condition in which cells or tissues undergo abnormal progressive growth. Colorectal cancer is cancer that occurs in the colon to rectum organs of humans. Alternative therapy for colorectal cancer treatment is the use of herbs such as Begonia medicinalis Ardi & D.C. Thomas. This study aimed to screen the bioactive compounds in the Begonia medicinalis Ardi & D.C. Thomas. extract and its potential as a colorectal cancer drug. This research consists of two stages, namely the extraction stage using the maceration method and the screening stage. The results showed that the extract of Begonia medicinalis Ardi & D.C. Thomas. positively contains flavonoids, alkaloids, and saponins. These bioactive compounds have potential activity as preventive and curative agents for colorectal cancer through several mechanisms, including suppressing oxidative stress, inhibiting CDK activity, suppressing intestinal inflammation, and increasing floranormal diversity and probiotic barrier activity in the intestine.

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Data unduhan belum tersedia.

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Unduhan

Diterbitkan

2024-11-01

Cara Mengutip

Ardiputra, M. A. ., Musjaya M. Guli, Andi Saifah, Santi, Bambang Sardi, Wafiq Nurfadilah, Mohammad Rivaldi Putra Pratama, & Afifah Islamia. (2024). Skrining fitokimia tumbuhan potensi obat kanker kolorektal Begonia medicinalis Ardi & D.C. Thomas. Jurnal Kedokteran Universitas Palangka Raya, 12(2). https://doi.org/10.37304/jkupr.v12i2.13207

Terbitan

Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya

Bagian

Jurnal Kedokteran

Lisensi

Hak Cipta (c) 2024 Jurnal Kedokteran Universitas Palangka Raya

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